Targets

Species

Concentration of polymyxin B

% inhibition^a

Protein serine/threonine kinase, AKT1

Human

10 μM

7

Protein serine/threonine kinase, Ca²⁺/calmodulin-Dep.II

Rat

10 μM

0

Protein serine/threonine kinase, GSK3β

Human

10 μM

0

Protein serine/threonine kinase, MLCK

Human

10 μM

4

Protein serine/threonine kinase, PKC, non-selective

Human

10 μM

0

Protein serine/threonine kinase, PKD2

Human

10 μM

42

Protein serine/threonine kinase, AMPK

Human

10 μM

0

Protein serine/threonine kinase, ROCK2

Human

10 μM

24

Protein serine/threonine kinase, p70S6K

Human

10 μM

0

Protein serine/threonine kinase, SGK1

Human

10 μM

0

Protein serine/threonine kinase, GRK5

Human

10 μM

79